Kit for the determination of hemopexin (HPX) on routine biochemical analyzers. The kit includes a reagent, a calibrator and a control.
Serum hemopexin levels reflect the amount of heme released into the blood. After the depletion of haptoglobin in episodes of acute hemolysis, Hemopexin intervenes, causing a further decrease that may even lead to depletion, indicating the release of a large amount of the heme group. It is therefore one of the diagnostic indicators of hemolytic anemia and clearly reflects the severity of the hemolytic episode.
A decrease in hemopexin levels is typically associated with a decrease in haptoglobin except in thalassemia, where there is no significant decrease in haptoglobin.
Applications for commonly used biochemical analyzers available (Advia®, Alinity C, AU®, Atellica™, cobas® C, Optilite®, Mindray and others).